Calculations based on glucose and insulin such as HOMA and QUICKI suggest an improvement in insulin sensitivity on ketogenic diets, even independently of weight loss. One study used a euglycemia hyperinsulinemia clamp and found an improvement in insulin sensitivity, but it was confounded by weight loss. Studies have generally found notably higher c-reactive protein on a ketogenic diet than control diet. Some studies have found no difference and some have found a greater reduction, one with considerably greater weight loss in the ketogenic group, and the other with unbalanced baseline levels.
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